The Prognostic Relevance of Computed Tomography-assessed Skeletal Muscle Index and Skeletal Muscle Radiation Attenuation in Patients With Gynecological Cancer

The evaluation of the whole skeletal muscle area at level third lumbar vertebra on computed tomography (CT) scans has often detected loss mass, defined as sarcopenia, and reduced radiation attenuation (SMRA) in patients with different malignancies. Baseline sarcopenia been 33.3%-51.8% advanced cervical cancer, 33.6%-50% those endometrial 11%-64% ovarian cancer. We reviewed literature data clinical relevance CT-assessed status gynecological Overall, baseline index SMRA have an uncertain prognostic relevance, whereas their changes during treatment usually correlate progression-free survival overall survival. Multicenter trials are strongly warranted to assess effects pharmacological agents physical exercise management damage